Past Research Staff 

 Dr. Stuart HODGETTS

    

Postdoctoral Research Fellow since joining January 1998 - December 2003 on a Parent Project Grant.

Now at Red's Spinal Cord Research Laboratory, UWA.
Present Project: Spinal cord repair using human bone marrow stromal cells.

Past Research Projects:
Cell biology, molecular biology and immunological techniques are being used to enhance the survival of normal donor male myoblasts after injection into dystrophic hosts in Myoblast Transfer Therapy (MTT) experiments, as a potential treatment for myopathies such as Duchenne Muscular Dystrophy (DMD). Techniques include tissue culture (primary culture and established cell lines), hybridoma technology, tissue sectioning (frozen and paraffin), fluorescence microscopy and image analysis (including time lapse), FACS analysis, immunodepletion, immunocytochemistry, PAGE and western blotting, quantitative DNA analysis using phosphorimaging systems (and analysis), Southern analysis, plasmid cloning and purification.
Link to Publications

Contact Details

 
Name: Stuart HODGETTS
Address: School of Anatomy and Human Biology (MD#309), The University of Western Australia, Crawley, Perth, W.A. 6009
Phone: (Work) : (08) 6488 2609
Facsimile: (08) 6488 1051
Email: hodgetts@cyllene.uwa.edu.au

Qualifications:

  • B.Sc. (Honours) (1985-1988), University of Essex, Biological Sciences, Essex, United Kingdom.
  • Ph.D. (1988-1991), "Novel Nuclear Proteins Detected by Autoimmune Sera", University of Essex, Essex, United Kingdom, Autoimmunity, Cell Biology And Molecular Biology.

Employment History:

1996 - 1997 Microbiology Department, University of Western Australia, QEII Medical Centre, Nedlands, 6907, Western Australia.
Postdoctoral Research Assistant.
Project: Mapping the flavivirus resistance gene in mice

1993 - 1995 Oklahoma Medical Research Foundation, Immunobiology & Cancer Program, Oklahoma City, Oklahoma, 73104, USA
Associate Research Scientist.
Project: Nuclear Matrix proteins that regulate Ig gene transcription

1992 - 1993 Biology Department, University of Essex, Wivenhoe Park, Colchester, Essex, CO4 3SQ, UK.
Postdoctoral Research Officer
Project: Gene transcription of Calvin cycle genes.


TEACHING EXPERIENCE
Supervisor for Ph.D. and final year Honours students in the School of Anatomy and Human Biology, University of Western Australia, Nedlands, Western Australia (1999-present).

Lecturer in 313 Molecular Biology and 313 Tissue Culture for final year Human Biology undergraduates at the Department of Anatomy and Human Biology, University of Western Australia, Nedlands, Western Australia (1998-present).

Lecturer in Developmental Biology and Reproduction at Essex University, U.K. (1993).

Assistant lecturer. Immunology Conference organised by the British Society of Immunology, University of Essex, U.K. (1990).


INVITED TALKS:

Hodgetts, S & Plant, G. (2004) Human Bone Marrow Stromal Cells in Spinal Cord Repair. Spinal Cord Society of Australia Meeting 22nd May, 2004.

Hodgetts, SI, & Grounds, MD (2002) A Role for Natural Killer Cells in the Rapid Death of Cultured Donor Myoblasts After Transplantation. Oral presentation, Xth International Congress on Neuromuscular Diseases, Vancouver, Canada, 7-12th July, 2002.


Grounds, MD & Hodgetts, SI, (2002) Cell Therapies Including Stem Cells for the Treatment of Muscular Dystrophies. Oral presentation and Special Education Poster, Xth Internatl Congress on Neuromuscular Diseases, Vancouver, Canada, 7-12th July, 2002.

Hodgetts, SI "The Immunobiology of Myoblast Transfer Therapy" 6th Symposium, Yonsei University Rehabilitation Institute of Muscular Disease, Yongdong Severance Hospital, Seoul, Korea (January, 2001)

Hodgetts, SI "Why Do Lonely Bachelor Myoblasts Die?" Centre for Immunology, St. Vincents Hospital, University of New South Wales, Sydney, Australia (December, 1999).


OCCASIONAL REVIEWER/EXAMINER

2002 Grant review for Austrian Science Fund
2001 Endocrinology
2001 Molecular and Cellular Endocrinology
2000 - 2001 Neuromuscular Disorders
1998 - 1999 Cell Transplantation
1999 - 2003 Grant Proposals


POSITIONS OF RESPONSIBILITY

Coordinator of Tissue Culture Facilities at the School of Anatomy and Human Biology, UWA, (2000-present). Implementation of policies and guidelines for Tissue Culture users in the School of Anatomy and Human Biology.

Coordinator of the Tissue Engineering Research Centre website (http://www.terc.uwa.edu.au/)

Committee member for the formation of the UWA Research Staff Association (2002 - present)

Executive Committee, School of Anatomy and Human Biology, UWA, (1999-2000 and 2003)

Assistant Health and Safety Officer, School of Anatomy and Human Biology, UWA, (2001 & 2003)

Focus Group member for UWA restructure, research level, at the School of Anatomy and Human Biology, UWA, (2002)

Founding committee member of the Biology Society at the University of Essex, United Kingdom (1992)

GRANTS HELD
2004 "Investigating the Role of Host Mast and Dendritic Cells on Donor Myoblast Survival in Myoblast Transfer Therapy". Hodgetts, S. UWA Research Grant $12,000.

GRANTS AWARDED
2001 - 2003 "Strategies to Optimize Myoblast Transfer Therapy." Stuart I. Hodgetts and Miranda D. Grounds. Duchenne Parent Project (Netherlands). Aktion Benni and Co. e.V. $77,256 AUS (Year 1), $76,170 AUS (Year 2)

2001 Ian Potter Travel Award. Tenth Anniversary Congress of the Cell Transplant Society. Keystone, Colorado, USA, October 14th-17th, 2001. $2,000 AUS.


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